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Tris(hydroxymethyl)amino Methane

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1000

tris; Pharmaceutical intermediates; Biological Buffers.

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Description
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Description

 

Chemical Name

Tris(hydroxymethyl)amino methane

Another name

Tris Base;Tris Buffer

CAS No.

77-86-1

Molecular formula

C4H11NO3

Molecular weight

121.14

Molecular Structure

 

Details

รูปร่าง

White crystalline powder

Assay  

99.9%min.

Melting point

168.0 – 171 ℃

Solubility(40% aq.)

Clear colorless solution

Heavy Metals

5ppm max

Loss on drying

0.2% max

pH value(5% aq.)

10.0-11.5

Iron ion (Fe3+)

1 ppm max.

Sulfate (SO42-)

10 ppm max.

Chloride(Cl-)

3 ppm max.

Ultraviolet absorbance 260 nm(20% aq.)

0.07 max.

Ultraviolet absorbance 260 nm(40% aq.)

0.07 max.

Ultraviolet absorbance 280 nm(40% aq.)

0.07 max.

Ultraviolet absorbance 290 nm(40% aq.)

0.05 max.

Ultraviolet absorbance 400 nm(40% aq.)

0.02 max.

Residue on ignition

0.05%max.

 

Main Application

Tris(hydroxymethyl)aminomethane could used in the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning Compounds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.

 

Tris(hydroxymethyl)aminomethane (commonly known as Tris) is a widely used buffering agent in various laboratory, pharmaceutical, and industrial applications. Its chemical formula is C4H11NO3, and it is a colorless, crystalline powder that is highly soluble in water. Tris is commonly used to maintain the pH stability of solutions, making it essential in biochemical and biological research.

 

Key Features & Benefits:

- Effective pH Buffer: Tris acts as an excellent buffer, maintaining the pH range of 7.0 to 9.0, ideal for many biochemical and molecular biology experiments.

- High Purity: Available in high-purity forms, ensuring reliable and consistent results in critical applications.

- Stability: Tris exhibits good thermal and chemical stability, making it suitable for use in various conditions.

- Versatility: It is widely used in applications ranging from protein analysis, enzyme activity studies, to DNA/RNA experiments.

- Biocompatibility: Non-toxic and safe for use in biological and pharmaceutical research.

 

Applications:

  1. Biochemical and Molecular Biology: Tris is a key component in buffer solutions, commonly used in electrophoresis, western blotting, PCR, and enzyme assays.
  2. Pharmaceutical Industry: Used in the formulation of injectable drugs and vaccine development to stabilize pH and enhance product performance.
  3. Industrial Applications: Used in water treatment, cosmetic formulations, and other chemical processes to maintain stable pH levels.

 

Packaging & Storage:

Tris is typically available in 25 kg bags or smaller packaging for laboratory use. It should be stored in a cool, dry place to maintain its stability and effectiveness.

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